The Effect of Spirulina Platensis Extract (Arthrospira platensis) on Enhancing Hemoglobin Levels in Pregnant Women

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DOI:

https://doi.org/10.36456/embrio.v16i1.8144

Keywords:

Hemoglobin, Pregnant Women, Spirulina platensis

Abstract

The prevalence of anemia is still relatively high in the world. The impacts of this case are abortion, premature birth, premature rupture of membranes, histitis, postpartum hemorrhage, low birth weight (LBW), risk of congenital defects, infection in babies, and even death. The objective of this research was to assess how the use of spirulina platensis extract influences the elevation of hemoglobin levels in expectant mothers. In this case, the method used is Quasi-Experiment through a pretest and posttest control group design with a sample of 60 participants, consisting of 30 participants and a control group of 30 participants. Furthermore, the group subjected to the intervention was provided with a remedy, which involved administering Spirulina platensis extract in the form of one 300 mg capsule once a day for 30 days and standard care, while the control group received standard care only. In addition, the sampling technique used is simple side random. The results of the Paired Sample T-test analysis in the intervention group during the pretest obtained a mean hemoglobin level of 9.63 with a standard deviation of 0.490, while during the post-test, obtained mean score of 10.93 with a standard deviation of 0.907 with a p-value of 0.000. Meanwhile, the analysis of the control group during the pretest obtained mean hemoglobin levels of 9.60 with a standard deviation of 0.498, while during the posttest, the mean score obtained was 9.70 with a standard deviation of 0.535 and p-value of 0.083. The difference between the mean hemoglobin levels during the posttest in the experimental and control groups showed m equal 10.93; SD equal 0.907 vs. m equal 9.70; SD equal 0.535, with a p-value of 0.000. Therefore, it is summed up that there was an increase in hemoglobin levels in pregnant women after the administration of Spirulina platensis extract. As input for the health workers, especially midwives, it is suggested to offer alternative therapeutic approaches for pregnant women suffering from anemia by applying Spirulina platensis.

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References

Agarwal, A. M., & Rets, A. (2021). Laboratory approach to the investigation of anemia in pregnancy. International Journal of Laboratory Hematology, 43(S1), 65–70. https://doi.org/10.1111/ijlh.13551 DOI: https://doi.org/10.1111/ijlh.13551

Ampofo, G. D., Tagbor, H., & Bates, I. (2018). Effectiveness of pregnant women’s active participation in their antenatal care for controlling malaria and anemia in pregnancy in Ghana: A cluster randomized controlled trial ISRTCTN88917252 ISRTCTN. Malaria Journal, 17(1), 1–15. https://doi.org/10.1186/s12936-018-2387-1 DOI: https://doi.org/10.1186/s12936-018-2387-1

Batool, A., Zafar, M. U., Abdullah, M., Mumtaz, H., Siddique, S., Sattar, S., & Rana, A. (2022). Comparative Effects of Spirulina with Iron Supplemented Sangobion Capsules among Anemic Females in Hafizabad. Pakistan Journal of Medical and Health Sciences, 16(5), 957–960. https://doi.org/10.53350/pjmhs22165957 DOI: https://doi.org/10.53350/pjmhs22165957

Bitam, A., & Aissaoui, O. (2020). Spirulina platensis, oxidative stress, and diabetes. Diabetes: Oxidative Stress and Dietary Antioxidants, 32, 325-331. https://doi.org/10.1016/B978-0-12-815776-3.00033-4 DOI: https://doi.org/10.1016/B978-0-12-815776-3.00033-4

Chaparro, C. M., & Suchdev, P. S. (2019). Anemia epidemiology, pathophysiology, and etiology in low- and middle-income countries. Annals of the New York Academy of Sciences, 1450(1), 15–31. https://doi.org/10.1111/NYAS.14092 DOI: https://doi.org/10.1111/nyas.14092

De Sá, S. A., Willner, E., Pereira, T. A. D., De Souza, V. R., Boaventura, G. T., & De Azeredo, V. B. (2015). Anemia in pregnancy: Impact on weight and in the development of anemia in newborn. Nutricion Hospitalaria, 32(5), 2071–2079. https://doi.org/10.3305/nh.2015.32.5.9186

ElFar, O. A., Billa, N., Lim, H. R., Chew, K. W., Cheah, W. Y., Munawaroh, H. S. H., Balakrishnan, D., & Show, P. L. (2022). Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes. Bioengineered, 13(6), 14681–14718. https://doi.org/10.1080/21655979.2022.2100863 DOI: https://doi.org/10.1080/21655979.2022.2100863

Fitriningsih, J., Stang, Sampara, N., Sudirman, J., Kusniyanto, R. E., & Lisnawati. (2021). The effect of consuming seaweed capsules of Spirulina on hemoglobin levels of pregnant women at Batua Public Health Center of Makassar. Enfermeria Clinica, 31, S697–S699. https://doi.org/10.1016/j.enfcli.2021.07.019 DOI: https://doi.org/10.1016/j.enfcli.2021.07.019

Georgieff, M. K. (2020). Iron deficiency in pregnancy. American Journal of Obstetrics and Gynecology, 223(4), 516–524. https://doi.org/10.1016/j.ajog.2020.03.006 DOI: https://doi.org/10.1016/j.ajog.2020.03.006

Gogna, S., Kaur, J., ORCID Icon, K. S., Prasad, R., Singh, J., Bhadariya, V., Kumar, P., & Departme, & S. J. (2022). Spirulina- An Edible Cyanobacterium with Potential Therapeutic Health Benefits and Toxicological Consequences. Journal of the American Nutrition Association, 42, 2023(6), 559–572. https://doi.org/10.1080/27697061.2022.2103852 DOI: https://doi.org/10.1080/27697061.2022.2103852

Grosshagauer, S., Kraemer, K., & Somoza, V. (2020). The True Value of Spirulina. Journal of Agricultural and Food Chemistry, 68(14), 4109–4115. https://doi.org/10.1021/acs.jafc.9b08251 DOI: https://doi.org/10.1021/acs.jafc.9b08251

Gusriani, Wahida, Nur Indah Noviyanti, N. (2022). The Effect of consuming seaweed on hemoglobin levels of pregnant women. International Journal of Health and Pharmaceutical. http://www.ijhp.net/index.php/IJHP/article/view/72/73 DOI: https://doi.org/10.51601/ijhp.v2i2.72

Jung, J., Rahman, M. M., Rahman, M. S., Swe, K. T., Islam, M. R., Rahman, M. O., & Akter, S. (2019). Effects of hemoglobin levels during pregnancy on adverse maternal and infant outcomes: a systematic review and meta-analysis. Annals of the New York Academy of Sciences, 1450(1), 69–82. https://doi.org/10.1111/NYAS.14112 DOI: https://doi.org/10.1111/nyas.14112

Karemoi, T. M., Mardiah, W., & Adistie, F. (2020). Factors Affecting Nutritional Status of Pregnant Women. Asian Community Health Nursing Research, 2(2), 39. https://doi.org/10.29253/achnr.2020.23958 DOI: https://doi.org/10.29253/achnr.2020.23958

Kuma, M. N., Tamiru, D., & Belachew, T. (2021). Hemoglobin Level and Associated Factors among Pregnant Women in Rural Southwest Ethiopia. BioMed Research International, 2021. https://doi.org/10.1155/2021/9922370 DOI: https://doi.org/10.1155/2021/9922370

Leal-esteban, L. C., Campos, R., Veauvy, M., Mascarenhas, B., Mhatre, M., Menon, S., Graz, B., & Weid, D. Von Der. (2021). Spirulina supplementation : A double-blind , randomized , comparative study in young anemic Indian women. Clinical Epidemiology and Global Health, 12(May), 100884. https://doi.org/10.1016/j.cegh.2021.100884 DOI: https://doi.org/10.1016/j.cegh.2021.100884

Marlina, D., & Nurhayati, F. (2020). The Effectiveness of Spirulina Compared with Iron Supplement on Anemia among Pregnant Women in Indonesia. International Journal of Caring Sciences, 13(3), 1783–1787. https://search.proquest.com/scholarly-journals/effectiveness-spirulina-compared-with-iron/docview/2480382379/se-2?accountid=13771

Means, R. T. (2020). Iron deficiency and iron deficiency anemia: Implications and impact in pregnancy, fetal development, and early childhood parameters. Nutrients, 12(2). https://doi.org/10.3390/nu12020447 DOI: https://doi.org/10.3390/nu12020447

Niang, K., Ndiaye, P., Faye, A., Tine, J. A. D., Diongue, F. B., Camara, M. D., Leye, M. M., & Tal-Dia, A. (2017). Spirulina Supplementation in Pregnant Women in the Dakar Region (Senegal). Open Journal of Obstetrics and Gynecology, 07(01), 147–154. https://doi.org/10.4236/ojog.2017.71016 DOI: https://doi.org/10.4236/ojog.2017.71016

Organização Mundial de Saúde. (2022). World health statistics 2022 (Monitoring health of the SDGs). http://apps.who.int/bookorders.

Othoo, D. A., Ochola, S., Kuria, E., & Kimiywe, J. (2021). Impact of Spirulina corn soy blend on Iron deficient children aged 6–23 months in Ndhiwa Sub-County Kenya: a randomized controlled trial. BMC Nutrition, 7(1), 1–12. https://doi.org/10.1186/s40795-021-00472-w DOI: https://doi.org/10.1186/s40795-021-00472-w

Sharma, A., & Datt, C. (2020). Supplementation effect of red seaweed powder on dry matter intake , body weight and feed conversion efficiency in crossbred cows. Journal of Entomology and Zoology Studies, 8(2), 1056–1059. https://www.entomoljournal.com/archives/?year=2020&vol=8&issue=2&ArticleId=6566

Smith, C., Teng, F., Branch, E., Chu, S., & Joseph, K. S. (2019). Maternal and Perinatal Morbidity and Mortality Associated with Anemia in Pregnancy. Obstetrics and Gynecology, 134(6), 1234–1244. https://doi.org/10.1097/AOG.0000000000003557 DOI: https://doi.org/10.1097/AOG.0000000000003557

Sorrenti, V., Castagna, D. A., Fortinguerra, S., Buriani, A., Scapagnini, G., & Willcox, D. C. (2021). Spirulina microalgae and brain health: A scoping review of experimental and clinical evidence. Marine Drugs, 19(6), 1–12. https://doi.org/10.3390/md19060293 DOI: https://doi.org/10.3390/md19060293

Sundararajan, S., & Rabe, H. (2021). Prevention of iron deficiency anemia in infants and toddlers. Pediatric Research, 89(1), 63–73. https://doi.org/10.1038/s41390-020-0907-5 DOI: https://doi.org/10.1038/s41390-020-0907-5

Sunuwar, D. R., Sangroula, R. K., Shakya, N. S., Yadav, R., Chaudhary, N. K., & Pradhan, P. M. S. (2019). Effect of nutrition education on hemoglobin level in pregnant women: A quasi-experimental study. PloS One, 14(3). https://doi.org/10.1371/JOURNAL.PONE.0213982 DOI: https://doi.org/10.1371/journal.pone.0213982

Tan, J., He, G., Qi, Y., Yang, H., Xiong, Y., Liu, C., Wang, W., Zou, K., Lee, A. H., Sun, X., & Liu, X. (2020). Prevalence of anemia and iron deficiency anemia in Chinese pregnant women (IRON WOMEN): a national cross-sectional survey. BMC Pregnancy and Childbirth, 20(1). https://doi.org/10.1186/S12884-020-03359-Z DOI: https://doi.org/10.1186/s12884-020-03359-z

Trotta, T., Porro, C., Cianciulli, A., & Panaro, M. A. (2022). Beneficial Effects of Spirulina Consumption on Brain Health. Nutrients, 14(3), 1–17. https://doi.org/10.3390/nu14030676 DOI: https://doi.org/10.3390/nu14030676

Wan, D., Wu, Q., & Kuča, K. (2016). Spirulina. Nutraceuticals: Efficacy, Safety and Toxicity, 569–583. https://doi.org/10.1016/B978-0-12-802147-7.00042-5 DOI: https://doi.org/10.1016/B978-0-12-802147-7.00042-5

Yadav, U. K., Ghimire, P., Amatya, A., & Lamichhane, A. (2021). Factors Associated with Anemia among Pregnant Women of Underprivileged Ethnic Groups Attending Antenatal Care at Provincial Level Hospital of Province 2, Nepal. Anemia, 2021. https://doi.org/10.1155/2021/8847472 DOI: https://doi.org/10.1155/2021/8847472

Yusof, J., Mahdy, Z. A., & Noor, R. M. (2016). Use of complementary and alternative medicine in pregnancy and its impact on obstetric outcome. Complementary Therapies in Clinical Practice, 25, 155–163. https://doi.org/10.1016/j.ctcp.2016.09.005 DOI: https://doi.org/10.1016/j.ctcp.2016.09.005

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Published

2024-05-31

How to Cite

Anggraeni, R. P. ., Kundarti, F. I., & Titisari, I. . (2024). The Effect of Spirulina Platensis Extract (Arthrospira platensis) on Enhancing Hemoglobin Levels in Pregnant Women. EMBRIO: Jurnal Kebidanan, 16(1), 7–17. https://doi.org/10.36456/embrio.v16i1.8144